Prof. Sunita Tiwari
Department of Physiology King Georg’s Medical University, Uttar Pradesh Lucknow, India
Title: Role of Vitamin D and nutritional supplementation in cognitive performance in senile dementia
Biography
Biography: Prof. Sunita Tiwari
Abstract
Introduction: Alzheimer’s disease is the most common form of age related cognitive impairment. Aim of the present study was to see the effect of vitamin D and calorie supplementation on cognitive function in elderly.
Material and methods: A total of 80 subjects were enrolled based on Mini Mental State Examination (MMSE) score < 24 and vitamin D deficiency. They were divided into two groups as Group A (case) and Group B (control), each group having 40 subjects. Both groups are on same medical treatment. Intervention (Vitamin D and calorie supplementation) was given to only Group A. The assessment of dementia was done by Mini Mental State Examination (MMSE) score. Nutritional assessment was done by Food frequency questionnaire (Designed by Indian Council of Medical Research). Oral nutritional supplementation was given twice daily for six month in addition to their usual diet. Two serving provide 600 Kcal. per day.120000 IU of cholecalciferol was given every month in the form of Calcirol granules.
Results: Gender, weight, height, BMI, residence and education were similar between two groups. A significant change in MMSE score was observed in both Group A and Group B from baseline to 3 & 6 months and from 3 to 6 months, however, mean change was higher in Group A than Group B.
Conclusion: In conclusion, vitamin D and calorie supplementation causes significant improvement in the cognitive performance in subjects with senile dementia.