Alzheimer’s Disease, Dementia Care Research and Awareness

Beta amyloid plaques and Neurofibrillary tangles of tau protein Pathology are prime suspects of neuronal cell death in Alzheimer’s it caused by accumulation of abnormally folded A-beta and tau proteins  and Plaques of small peptides 39–43 amino acids to  form Beta-amyloid which comprises amyloid precursor protein (APP) and a transmembrane protein that pierce the neuron's membrane. It later forms a fibrils of amyloid protein clump which get deposited in neurons to form a dense senile plaques, amyloid fibrils disrupts the cell’s calcium ions homeostasis and induces apoptosis of neurons which results in neurodegeneration affecting brain functioning.

More than 400 clinical trials are presently looking at new treatments for Alzheimer’s disease (AD) and many of them are actively recruiting. Many of the researches are based on decreasing the toxic effects of amyloid-beta in the brain, targeting amyloid production, blocking the accumulation of amyloid-beta into plaques, Aiming at Tau, Improving Cognition with Serotonin and Dietary Supplements.

Vascular dementia is the wider term for dementia associated with brain damage from impaired blood flow to the brain. The various types of dementia are Single-infarct, Multi-infarct dementia, Subcortical vascular dementia (Binswanger's disease), and Mixed dementia. Its clinical symptoms are Problems with planning or organising, concentrating, including short periods of sudden confusion and Memory, language and visuospatial skills also get affected.

Anyone can be affected by Vascular dementia, but several factors increase the risk. These include: High blood pressure, Smoking, Diabetes, High cholesterol, History of mild warning strokes, Evidence of disease in arteries elsewhere and Heart rhythm abnormalities, while no remedy can reverse the damage that has already been occurred, treatment to prevent extra strokes may be very essential.

Gerontology is scientific study of aging process and concerned with physical, mental, and social aspects and implications of aging. The field of gerontology is actually quite broader, containing many professionals who focus on different aspects of aging and development.

Gerontologists include practitioners and researchers in the areas fields of nursing, medicine, criminology, biology, social work, physical and occupational therapy, psychology, sociology, psychiatry, dentistry, economics, political science, architecture, geography, pharmacy, public health, housing, and anthropology. There are several theories of aging but none has been accepted.

Geriatric health care practice also known as "elder care health management, it is a process of planning and coordinating care of the old aged individuals and others with physical and/or mental abilities to meet their long term care needs, enhance their quality of life, and carried their independence for as long as possible. It involves in working with persons of old age and their families in managing, rendering and furnishing various types of health and social care services.

Awareness is attention plus working memory, and Awareness has a quite specific definition, Neural systems that controls and regulate to attenuate awareness in humans whose central and peripheral nervous system provides more instructions than cognitive sites in the brain can assimilate.

Cognitive neuroscience is scientific study of neural mechanisms which connects cognitive psychology, neurobiology, neurology, mathematics, physics, linguistics, philosophy and computer science, as well as artificial intelligence, which includes psychophysical experiments, electrophysiological studies of neural systems, functional neuroimaging, and increasingly  cognitive genomics and behavioural genetics.Artificial Intelligence (AI) entails the study of cognitive phenomena in machines one of the realistic desires of artificial intelligence is to put aspects of human intelligence in computer systems.

Neurodegeneration marked by gradual loss of neuronal structure and its functions, including death of neurons, The most common neurodegenerative diseases are Alzheimer’s disease and Parkinson’s disease. Degenerative nerve diseases have an effect on many of your body's activities, which includes balance, movement, talking, respiration, and coronary heart function, many of these diseases are genetic, sometimes the reason is a scientific condition which include alcoholism, a tumour, or a stroke, other reasons can also include pollution, chemicals, and viruses, sometimes the purpose is not known. Degenerative nerve diseases include Alzheimer's disease, Amyotrophic lateral sclerosis, Friedreich's ataxia, Huntington's disease, Lewy body disease, Parkinson's disease and Spinal muscular atrophy.

Memory Disorders is a collective term marked by damage or injury of neuroanatomical structures that affects the storage, retention and memory recall process of brain, The major causes for memory impairment are Brain strokes, High blood pressure, Medications, Diabetes, Brain trauma or head injury and nutritional deficiencies.

A various types of diseases in which memory storage get halted are Alzheimer's Disease, Corticobasal Degeneration, Creutzfeldt-Jakob Disease, Frontotemporal Dementia, Huntington's Disease, Lewy Body Dementia, Mild Cognitive Impairment, Progressive Supranuclear Palsy and Vascular Dementia.

Neuro-immunology is a vast branch of science that combines the nervous system and immune system together. This field assist in regulating thermogenesis, behavior, sleep, and mood which can be tormented by pro-inflammatory cytokines released by means of activated macrophages and monocytes throughout infection. Neuroinflammation and neuroimmune activation were shown to play a role in the aetiology of a variety of neurological problems which includes stroke, Parkinson's and Alzheimer's disease, multiple sclerosis,https://alzheimers.global-summit.com/ pain, and AIDS-related dementia, however  cytokines and chemokines also modulate CNS function in the absence of overt immunological, physiological, or mental challenges.

Movement disorders refers to a group of nervous system characterized of movement disorders are clinical syndromes with both an excess of motion or a paucity of voluntary and involuntary actions. Individuals with a motion disorder suffer from a breakdown in the normal flow of neurological messages and this result in involuntary muscle motion. Common types of movement disorders are Ataxia, Cervical dystonia, Chorea, Dystonia, Functional movement disorder, Multiple system atrophy, Myoclonus, Progressive supranuclear palsy, Restless legs syndrome, Tardive dyskinesia, Tourette syndrome, Tremor and Wilson's disease.

Health nursing is a well experienced and qualified nurse in mental health that cares for people of all ages with mental conditions like schizophrenia, psychosis, bipolar disorder, depression, anxiety, dementia, and many more. Mental health nurses, especially CPNs, are involved in counselling, which can range from casual chats through to based, one-to-one psychotherapy sessions.

The major duty of a psychiatric nurse is to maintain a healthy and positive therapeutic relationship with patients and direct communication is necessary for developing it.

Dementia is a chronic condition of the mental health caused by brain disease or injury marked by memory inabilities, personality impairments, and impaired reasoning. Dementia care practice is a process optimizing patient’s quality of life, functional independence, health, and wellbeing, all of whom may additionally struggle physically, emotionally, and financially from their diverse relationships to the sickness.

The importance of palliative care extends far past ‘end-of-lifestyles treatment for most cancers sufferers, There are some of crucial regions for palliative care exactly in neurology and a regularly developing call for it – now not least because of ever higher lifestyles expectancy charges worldwide.

Example of patients with glioblastoma with this progressive disorder, the need for palliative care constantly will increase. It’s far tough to mention for sure the factor in time at which palliative care need so be initiated, experience shows that factors of palliative medicinal drug are employed and primarily, organized early on in the path of the disorder, even at some point of oncological treatment.

A stroke or cerebrovascular accident is the unexpectedly growing loss of brain functions because of disturbance in the blood supply to the brain, caused by a blocked or burst blood vessel. In emergency conditions neurological damage get worsened which may results in bleeding (haemorrhagic strokes) and death. The strokes like ischemic stroke, thrombotic stroke, haemorrhagic stroke, intracerebral haemorrhage and subarachnoid haemorrhage are the various types of neuro strokes.

Symptoms includes sudden onset of numbness, weakness, confusion, difficulty speaking, vision loss, dizziness, imbalance and severe headache. It can be prevented by monitoring diet, regulating blood pressure and diabetes levels, physical work out and quitting smoking.

Mood disorders are a set of illnesses that presents a serious change in mood. The major categories are Depression and Bipolar disorders. The subject may experience euphoric, mania, hyperactive, over inflated ego, persistent depressive disorder and seasonal depressive disorders. The Psychiatric Disorders and Mood Disorders is interlinked in its nature it means that the subject with psychiatric disorders has a chance of developing Depression. The other mood disorders are Cyclothymic disorder, premenstrual dysphoric disorder, Persistent depressive disorder (dysthymia), Disruptive mood dysregulation disorder and Depression induced by substance use or medication.